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Antibody-drug conjugates in clinical trials for lymphoid malignancies and multiple myeloma
Antibody-drug conjugates (ADC) represent a distinct family of chemoimmunotherapy agents. ADCs are composed of monoclonal antibodies conjugated to cytotoxic payloads via specialized chemical linkers. ADCs therefore combine the immune therapy with targeted chemotherapy. Due to the distinct biomarkers...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734251/ https://www.ncbi.nlm.nih.gov/pubmed/31500657 http://dx.doi.org/10.1186/s13045-019-0786-6 |