Logical modelling reveals the PDC-PDK interaction as the regulatory switch driving metabolic flexibility at the cellular level

BACKGROUND: Metabolic flexibility is the ability of an organism to switch between substrates for energy metabolism, in response to the changing nutritional state and needs of the organism. On the cellular level, metabolic flexibility revolves around the tricarboxylic acid cycle by switching acetyl c...

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Detalles Bibliográficos
Autores principales: Tareen, Samar HK, Kutmon, Martina, Arts, Ilja CW, de Kok, Theo M, Evelo, Chris T, Adriaens, Michiel E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734263/
https://www.ncbi.nlm.nih.gov/pubmed/31516637
http://dx.doi.org/10.1186/s12263-019-0647-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734263/
https://www.ncbi.nlm.nih.gov/pubmed/31516637
http://dx.doi.org/10.1186/s12263-019-0647-5

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