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Proper evaluation of chemical cross-linking-based spatial restraints improves the precision of modeling homo-oligomeric protein complexes

BACKGROUND: The function of oligomeric proteins is inherently linked to their quaternary structure. In the absence of high-resolution data, low-resolution information in the form of spatial restraints can significantly contribute to the precision and accuracy of structural models obtained using comp...

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Detalles Bibliográficos
Autores principales: Gaber, Aljaž, Gunčar, Gregor, Pavšič, Miha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734309/
https://www.ncbi.nlm.nih.gov/pubmed/31500562
http://dx.doi.org/10.1186/s12859-019-3032-x