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Proper evaluation of chemical cross-linking-based spatial restraints improves the precision of modeling homo-oligomeric protein complexes
BACKGROUND: The function of oligomeric proteins is inherently linked to their quaternary structure. In the absence of high-resolution data, low-resolution information in the form of spatial restraints can significantly contribute to the precision and accuracy of structural models obtained using comp...
Autores principales: | Gaber, Aljaž, Gunčar, Gregor, Pavšič, Miha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734309/ https://www.ncbi.nlm.nih.gov/pubmed/31500562 http://dx.doi.org/10.1186/s12859-019-3032-x |
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