Semi-synthesis of β-keto-1,2,3-triazole derivatives from ethinylestradiol and evaluation of the cytotoxic activity

In this study, we report our contribution to the application of the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction for the synthesis of β-keto-1,2,3-triazole derivatives 3a-f from ethinylestradiol and their application in the inhibition of two human cancer cells lines: human breast ade...

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Detalles Bibliográficos
Autores principales: Queiroz, Thayane M., Orozco, Erika V.M., Silva, Valdenizia R., Santos, Luciano S., Soares, Milena B.P., Bezerra, Daniel P., Porto, André L.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734327/
https://www.ncbi.nlm.nih.gov/pubmed/31517128
http://dx.doi.org/10.1016/j.heliyon.2019.e02408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734327/
https://www.ncbi.nlm.nih.gov/pubmed/31517128
http://dx.doi.org/10.1016/j.heliyon.2019.e02408

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