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ROS/TRPA1/CGRP signaling mediates cortical spreading depression

OBJECTIVES: The transient receptor potential ankyrin A 1 (TRPA1) channel and calcitonin gene-related peptide (CGRP) are targets for migraine prophylaxis. This study aimed to understand their mechanisms in migraine by investigating the role of TRPA1 in cortical spreading depression (CSD) in vivo and...

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Detalles Bibliográficos
Autores principales: Jiang, Liwen, Ma, Dongqing, Grubb, Blair D., Wang, Minyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734415/
https://www.ncbi.nlm.nih.gov/pubmed/30841847
http://dx.doi.org/10.1186/s10194-019-0978-z