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Targeting microglia with lentivirus and AAV: Recent advances and remaining challenges

Microglia have emerged as a critical component of neurodegenerative diseases. Genetic manipulation of microglia can elucidate their functional impact in disease. In neuroscience, recombinant viruses such as lentiviruses and adeno-associated viruses (AAVs) have been successfully used to target variou...

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Detalles Bibliográficos
Autores principales: Maes, Margaret E., Colombo, Gloria, Schulz, Rouven, Siegert, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers Ireland 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734419/
https://www.ncbi.nlm.nih.gov/pubmed/31158432
http://dx.doi.org/10.1016/j.neulet.2019.134310