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Targeting microglia with lentivirus and AAV: Recent advances and remaining challenges
Microglia have emerged as a critical component of neurodegenerative diseases. Genetic manipulation of microglia can elucidate their functional impact in disease. In neuroscience, recombinant viruses such as lentiviruses and adeno-associated viruses (AAVs) have been successfully used to target variou...
Autores principales: | Maes, Margaret E., Colombo, Gloria, Schulz, Rouven, Siegert, Sandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Scientific Publishers Ireland
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734419/ https://www.ncbi.nlm.nih.gov/pubmed/31158432 http://dx.doi.org/10.1016/j.neulet.2019.134310 |
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