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Three Optimized Methods for In Situ Quantification of Progenitor Cell Proliferation in Embryonic Kidneys Using BrdU, EdU, and PCNA

BACKGROUND: Nephron progenitor cells derived from the metanephric mesenchyme undergo a complex balance of self-renewal and differentiation throughout kidney development to give rise to the mature nephron. Cell proliferation is an important index of progenitor population dynamics. However, accurate a...

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Detalles Bibliográficos
Autores principales: O’Hara, Rosalie E., Arsenault, Michel G., Esparza Gonzalez, Blanca P., Patriquen, Ashley, Hartwig, Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734617/
https://www.ncbi.nlm.nih.gov/pubmed/31523438
http://dx.doi.org/10.1177/2054358119871936