An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings

BACKGROUND: Mendelian randomization (MR) is a powerful tool in epidemiology that can be used to estimate the causal effect of an exposure on an outcome in the presence of unobserved confounding, by utilizing genetic variants that are instrumental variables (IVs) for the exposure. This has been exten...

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Detalles Bibliográficos
Autores principales: Sanderson, Eleanor, Davey Smith, George, Windmeijer, Frank, Bowden, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Mendelian Randomization
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734942/
https://www.ncbi.nlm.nih.gov/pubmed/30535378
http://dx.doi.org/10.1093/ije/dyy262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734942/
https://www.ncbi.nlm.nih.gov/pubmed/30535378
http://dx.doi.org/10.1093/ije/dyy262

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