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PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells

Pancreatic cancer (PC) is one of the most lethal diseases, and effective treatment of PC patients remains an enormous challenge. Rocaglamide A (Roc-A), a bioactive molecule extracted from the plant Aglaia elliptifolia, has aroused considerable attention as a therapeutic choice for numerous cancer tr...

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Detalles Bibliográficos
Autores principales: Zhao, Chunle, He, Ruizhi, Shen, Ming, Zhu, Feng, Wang, Min, Liu, Yuhui, Chen, Hua, Li, Xu, Qin, Renyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735223/
https://www.ncbi.nlm.nih.gov/pubmed/31551778
http://dx.doi.org/10.3389/fphar.2019.00968