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CD38 Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD(+)/Sirt1 Signaling Pathway

Our previous research showed that CD38 played vital roles in Ang-II induced hypertrophy and high fat diet induced heart injury. However, the role of CD38 in heart aging is still unknown. In the present study, we reported that CD38 knockdown significantly protected cardiomyocytes from D-galactose (D-...

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Detalles Bibliográficos
Autores principales: Wang, Ling-Fang, Cao, Qing, Wen, Ke, Xiao, Yun-Fei, Chen, Ting-Tao, Guan, Xiao-Hui, Liu, Yu, Zuo, Li, Qian, Yi-Song, Deng, Ke-Yu, Xin, Hong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735286/
https://www.ncbi.nlm.nih.gov/pubmed/31551807
http://dx.doi.org/10.3389/fphys.2019.01125