Cargando…

CD38 Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD(+)/Sirt1 Signaling Pathway

Our previous research showed that CD38 played vital roles in Ang-II induced hypertrophy and high fat diet induced heart injury. However, the role of CD38 in heart aging is still unknown. In the present study, we reported that CD38 knockdown significantly protected cardiomyocytes from D-galactose (D-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ling-Fang, Cao, Qing, Wen, Ke, Xiao, Yun-Fei, Chen, Ting-Tao, Guan, Xiao-Hui, Liu, Yu, Zuo, Li, Qian, Yi-Song, Deng, Ke-Yu, Xin, Hong-Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735286/ https://www.ncbi.nlm.nih.gov/pubmed/31551807 http://dx.doi.org/10.3389/fphys.2019.01125

Ejemplares similares

CD38 Deficiency Alleviates Diabetic Cardiomyopathy by Coordinately Inhibiting Pyroptosis and Apoptosis
por: Wang, Ling-Fang, et al.
Publicado: (2023)

CD38-NAD(+)-Sirt1 axis in T cell immunotherapy
por: Chatterjee, Shilpak, et al.
Publicado: (2019)

CD38 Deficiency Protects the Heart from Ischemia/Reperfusion Injury through Activating SIRT1/FOXOs-Mediated Antioxidative Stress Pathway
por: Guan, Xiao-Hui, et al.
Publicado: (2016)

Macrophage Immunometabolism and Inflammaging: Roles of Mitochondrial Dysfunction, Cellular Senescence, CD38, and NAD
por: Yarbro, Johnathan R., et al.
Publicado: (2020)

Downregulation of Sirt6 by CD38 promotes cell senescence and aging
por: Zhou, Hongji, et al.
Publicado: (2022)

Curcumin Alleviates D-Galactose-Induced Cardiomyocyte Senescence by Promoting Autophagy via the SIRT1/AMPK/mTOR Pathway
por: Yang, Lei, et al.
Publicado: (2022)

CD38 Deficiency Protects Mice from High Fat Diet-Induced Nonalcoholic Fatty Liver Disease through Activating NAD(+)/Sirtuins Signaling Pathways-Mediated Inhibition of Lipid Accumulation and Oxidative Stress in Hepatocytes
por: Xie, Lin, et al.
Publicado: (2021)

CD38 deficiency suppresses adipogenesis and lipogenesis in adipose tissues through activating Sirt1/PPARγ signaling pathway
por: Wang, Ling‐Fang, et al.
Publicado: (2017)

Nicotinamide Mononucleotide Supplementation Improves Mitochondrial Dysfunction and Rescues Cellular Senescence by NAD(+)/Sirt3 Pathway in Mesenchymal Stem Cells
por: Wang, Huan, et al.
Publicado: (2022)

CD38 Deficiency Promotes Inflammatory Response through Activating Sirt1/NF-κB-Mediated Inhibition of TLR2 Expression in Macrophages
por: Qian, Yisong, et al.
Publicado: (2018)

CD38 is methylated in prostate cancer and regulates extracellular NAD(+)
por: Mottahedeh, Jack, et al.
Publicado: (2018)

Tangshen Formula Alleviates Hepatic Steatosis by Inducing Autophagy Through the AMPK/SIRT1 Pathway
por: Wang, Yan, et al.
Publicado: (2019)

CD38 regulates ovarian function and fecundity via NAD(+) metabolism
por: Perrone, Rosalba, et al.
Publicado: (2023)

Function and Mechanism of Trimetazidine in Myocardial Infarction-Induced Myocardial Energy Metabolism Disorder Through the SIRT1–AMPK Pathway
por: Luo, Xiu-ying, et al.
Publicado: (2021)

CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice
por: Gan, Lu, et al.
Publicado: (2021)

Complex I deficiency in m.3243A>G fibroblasts is alleviated by reducing NADH accumulation
por: Liufu, Tongling, et al.
Publicado: (2023)

β-hydroxybutyrate Alleviates Learning and Memory Impairment Through the SIRT1 Pathway in D-Galactose-Injured Mice
por: Yang, Xiaojing, et al.
Publicado: (2021)

Feasibility of NAD(P)/NAD(P)H as redox agents in enzymatic plasmonic gold nanostar assays for galactose quantification
por: Munyayi, Tozivepi Aaron, et al.
Publicado: (2023)

Inflammatory Drivers of Cardiovascular Disease: Molecular Characterization of Senescent Coronary Vascular Smooth Muscle Cells
por: Stojanović, Stevan D., et al.
Publicado: (2020)

MiR-34a suppression targets Nampt to ameliorate bone marrow mesenchymal stem cell senescence by regulating NAD(+)-Sirt1 pathway
por: Pi, Chenchen, et al.
Publicado: (2021)

Targeting CD38 alleviates tumor-induced immunosuppression
por: Tai, Yu-Tzu, et al.
Publicado: (2017)

Targeting CD38-dependent NAD(+) metabolism to mitigate multiple organ fibrosis
por: Shi, Bo, et al.
Publicado: (2020)

CD38 promotes angiotensin II‐induced cardiac hypertrophy
por: Guan, Xiao‐Hui, et al.
Publicado: (2017)

17β-Estradiol Promotes Apoptosis in Airway Smooth Muscle Cells Through CD38/SIRT1/p53 Pathway
por: Liu, Yu, et al.
Publicado: (2018)

Flavonoid Apigenin Is an Inhibitor of the NAD(+)ase CD38: Implications for Cellular NAD(+) Metabolism, Protein Acetylation, and Treatment of Metabolic Syndrome
por: Escande, Carlos, et al.
Publicado: (2013)

Protective Effect of SIRT1 Activator on the Knee With Osteoarthritis
por: Zhou, Zhenquan, et al.
Publicado: (2021)

SIRT1-dependent restoration of NAD+ homeostasis after increased extracellular NAD+ exposure
por: Buonvicino, Daniela, et al.
Publicado: (2021)

Effect of circadian rhythm on NAD and other metabolites in human brain
por: Cuenoud, Bernard, et al.
Publicado: (2023)

Tumor growth of neurofibromin-deficient cells is driven by decreased respiration and hampered by NAD(+) and SIRT3
por: Masgras, Ionica, et al.
Publicado: (2022)

MiR-22 Inhibition Alleviates Cardiac Dysfunction in Doxorubicin-Induced Cardiomyopathy by Targeting the sirt1/PGC-1α Pathway
por: Wang, Runze, et al.
Publicado: (2021)

Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1
por: Mao, Shuai, et al.
Publicado: (2018)

Nicotinamide phosphoribosyltransferase postpones rat bone marrow mesenchymal stem cell senescence by mediating NAD(+)–Sirt1 signaling
por: Pi, Chenchen, et al.
Publicado: (2019)

D-Galactose Induces Chronic Oxidative Stress and Alters Gut Microbiota in Weaned Piglets
por: Han, Hui, et al.
Publicado: (2021)

CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1
por: Hu, Xuebin, et al.
Publicado: (2018)

NAD(H) recycling activity of an engineered bifunctional enzyme galactose dehydrogenase/lactate dehydrogenase
por: Prachayasittikul, Virapong, et al.
Publicado: (2006)

Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD(+)
por: Iannetti, Eligio F., et al.
Publicado: (2018)

EP3 Blockade Adds to the Effect of TP Deficiency in Alleviating Endothelial Dysfunction in Atherosclerotic Mouse Aortas
por: Hu, Chuangjia, et al.
Publicado: (2019)

Mechanism of CD38 via NAD(+) in the Development of Non-alcoholic Fatty Liver Disease
por: Dong, Min, et al.
Publicado: (2023)

Interleukin‐38 alleviates cardiac remodelling after myocardial infarction
por: Wei, Yuzhen, et al.
Publicado: (2019)

Retraction: MiR-22 inhibition alleviates cardiac dysfunction in doxorubicin-induced cardiomyopathy by targeting the sirt1/PGC-1α pathway
por: Frontiers Editorial Office,
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rniuo49gqtgbhdarm6bsut48ue