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The inhibition of Nrf2 accelerates renal lipid deposition through suppressing the ACSL1 expression in obesity-related nephropathy

Background: Obesity has become a worldwide epidemic, and the incidence of obesity is increasing year by year. Obesity-related nephropathy (ORN) is a common kidney complication of obesity. Long-chain acyl-CoA synthetases-1, (ACSL1), is a key enzyme in the oxidative metabolism of fatty acids in mitoch...

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Detalles Bibliográficos
Autores principales: Chen, Yinyin, He, Liyu, Yang, Yiya, Chen, Ying, Song, Yanran, Lu, Xi, Liang, Yumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735294/
https://www.ncbi.nlm.nih.gov/pubmed/31488013
http://dx.doi.org/10.1080/0886022X.2019.1655450