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Stimuli-responsive nanodrug self-assembled from amphiphilic drug-inhibitor conjugate for overcoming multidrug resistance in cancer treatment

Severe multidrug resistance (MDR) often develops in the process of chemotherapy for most small molecule anticancer drugs, which results in clinical chemotherapy failures. Methods: Here, a nanodrug is constructed through the self-assembly of amphiphilic drug-inhibitor conjugates (ADIC) containing a r...

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Detalles Bibliográficos
Autores principales: Huang, Ping, Wang, Guanchun, Su, Yue, Zhou, Yongfeng, Huang, Wei, Zhang, Rong, Yan, Deyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735370/
https://www.ncbi.nlm.nih.gov/pubmed/31534517
http://dx.doi.org/10.7150/thno.36163