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Biodegradable, pH-Sensitive Hollow Mesoporous Organosilica Nanoparticle (HMON) with Controlled Release of Pirfenidone and Ultrasound-Target-Microbubble-Destruction (UTMD) for Pancreatic Cancer Treatment

The dense extracellular matrix (ECM) and hypovascular networks were often found in solid pancreatic tumors form an impenetrable barrier, leading to limited uptake of chemotherapeutics and thus undesirable treatment outcomes. Methods: A biodegradable nanoplatform based on hollow mesoporous organosili...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Wu, Jianrong, Niu, Shiwei, Sun, Ting, Li, Fan, Bai, Yun, Jin, Lifang, Lin, Lizhou, Shi, Qiusheng, Zhu, Li-Min, Du, Lianfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735371/
https://www.ncbi.nlm.nih.gov/pubmed/31534533
http://dx.doi.org/10.7150/thno.36135