Inhibition of HSP90β Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System

Rationale: Heat shock protein 9 (HSP90) are a family of the most highly expressed cellular proteins and attractive drug targets against cancer, neurodegeneration diseases, etc. HSP90 proteins have also been suggested to be linked to lipid metabolism. However, the specific function of HSP90 paralogs,...

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Detalles Bibliográficos
Autores principales: Zheng, Zu-Guo, Zhang, Xin, Liu, Xiao-Xiao, Jin, Xiu-Xiu, Dai, Lunzhi, Cheng, Hui-Min, Jing, Dan, Thu, Pyone Myat, Zhang, Mu, Li, Hongyang, Zhu, Jing, Liu, Chang, Xue, Bin, Li, Yu, Chen, Ligong, Peng, Cheng, Zhu, Weiliang, Wang, Lin, Liu, Junli, Li, Hui-Jun, Li, Ping, Xu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735373/
https://www.ncbi.nlm.nih.gov/pubmed/31534518
http://dx.doi.org/10.7150/thno.36505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735373/
https://www.ncbi.nlm.nih.gov/pubmed/31534518
http://dx.doi.org/10.7150/thno.36505

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