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Co-delivery of VEGF siRNA and Etoposide for Enhanced Anti-angiogenesis and Anti-proliferation Effect via Multi-functional Nanoparticles for Orthotopic Non-Small Cell Lung Cancer Treatment

Targeting tumor angiogenesis pathway via VEGF siRNA (siVEGF) has shown great potential in treating highly malignant and metastatic non-small cell lung cancer (NSCLC). However, anti-angiogenic monotherapy lacked sufficient antitumor efficacy which suffered from malignant tumor proliferation. Therefor...

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Detalles Bibliográficos
Autores principales: Li, Fang, Wang, Yu, Chen, Wei-liang, Wang, Dan-dan, Zhou, Ye-juan, You, Ben-gang, Liu, Yang, Qu, Chen-xi, Yang, Shu-di, Chen, Meng-tian, Zhang, Xue-nong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735374/
https://www.ncbi.nlm.nih.gov/pubmed/31534526
http://dx.doi.org/10.7150/thno.32416