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Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets

The human skin is an attractive anti-tumor vaccination site due to the vast network of dendritic cell (DC) subsets that carry antigens to the draining lymph nodes and stimulate tumor specific CD4(+) and CD8(+) T cells in. Specific vaccine delivery to skin DC can be accomplished by targeting glycan c...

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Detalles Bibliográficos
Autores principales: Duinkerken, Sanne, Horrevorts, Sophie K., Kalay, Hakan, Ambrosini, Martino, Rutte, Lisa, de Gruijl, Tanja D., Garcia-Vallejo, Juan J., van Kooyk, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735376/
https://www.ncbi.nlm.nih.gov/pubmed/31534520
http://dx.doi.org/10.7150/thno.35059