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Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells
PPARγ is a pharmacological target in inflammatory and metabolic diseases. Upon agonistic treatment or following antagonism, binding of co-factors is altered, which consequently affects PPARγ-dependent transactivation as well as its DNA-independent properties. Therefore, establishing techniques to ch...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735382/ https://www.ncbi.nlm.nih.gov/pubmed/31534496 http://dx.doi.org/10.7150/thno.29367 |