Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells

PPARγ is a pharmacological target in inflammatory and metabolic diseases. Upon agonistic treatment or following antagonism, binding of co-factors is altered, which consequently affects PPARγ-dependent transactivation as well as its DNA-independent properties. Therefore, establishing techniques to ch...

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Detalles Bibliográficos
Autores principales: Trümper, Verena, von Knethen, Andreas, Preuß, Annegret, Ermilov, Eugeny, Hackbarth, Steffen, Kuchler, Laura, Gunne, Sandra, Schäfer, Anne, Bornhütter, Tobias, Vereb, György, Ujlaky-Nagy, Lázló, Brüne, Bernhard, Röder, Beate, Schindler, Michael, Parnham, Michael J., Knape, Tilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735382/
https://www.ncbi.nlm.nih.gov/pubmed/31534496
http://dx.doi.org/10.7150/thno.29367

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