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Tumor-derived DNA from pleural effusion supernatant as a promising alternative to tumor tissue in genomic profiling of advanced lung cancer

Pleural effusion (PE) is commonly observed in advanced lung cancer and was suggested to contain both cell-free tumor DNA and tumor cells. Molecular profiling of PE represents a minimally invasive approach of detecting tumor driver mutations for clinical decision making, especially when tumor tissues...

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Detalles Bibliográficos
Autores principales: Tong, Lin, Ding, Ning, Tong, Xiaoling, Li, Jiamin, Zhang, Yong, Wang, Xiaodan, Xu, Xiaobo, Ye, Maosong, Li, Chun, Wu, Xue, Bao, Hairong, Zhang, Xin, Hong, Qunying, Song, Yuanlin, Shao, Yang W., Bai, Chunxue, Zhou, Jian, Hu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735385/
https://www.ncbi.nlm.nih.gov/pubmed/31534501
http://dx.doi.org/10.7150/thno.34070