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Multi-omics profiling reveals key signaling pathways in ovarian cancer controlled by STAT3

Inhibiting STAT3 signaling reduces tumor progression, metastasis and chemoresistance, however the precise molecular mechanism has not been fully delineated in ovarian cancer. Methods: In this study, we generated STAT3 knockout (KO) ovarian cancer cell lines. Effects of STAT3 KO on cell proliferation...

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Detalles Bibliográficos
Autores principales: Lu, Tiangong, Bankhead, Armand, Ljungman, Mats, Neamati, Nouri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735387/
https://www.ncbi.nlm.nih.gov/pubmed/31534498
http://dx.doi.org/10.7150/thno.33444