Cargando…

Multi-omics profiling reveals key signaling pathways in ovarian cancer controlled by STAT3

Inhibiting STAT3 signaling reduces tumor progression, metastasis and chemoresistance, however the precise molecular mechanism has not been fully delineated in ovarian cancer. Methods: In this study, we generated STAT3 knockout (KO) ovarian cancer cell lines. Effects of STAT3 KO on cell proliferation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Tiangong, Bankhead, Armand, Ljungman, Mats, Neamati, Nouri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735387/ https://www.ncbi.nlm.nih.gov/pubmed/31534498 http://dx.doi.org/10.7150/thno.33444

Ejemplares similares

Up-regulation of hypoxia-inducible factor antisense as a novel approach to treat ovarian cancer
por: Lu, Tiangong, et al.
Publicado: (2020)

Current Challenges and Opportunities in Treating Glioblastoma
por: Shergalis, Andrea, et al.
Publicado: (2018)

Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes
por: Xu, Shili, et al.
Publicado: (2019)

Multi-Omics Analysis Identifying Key Biomarkers in Ovarian Cancer
por: Li, Ju-Yueh, et al.
Publicado: (2020)

Multi-omics profiling reveals microRNA-mediated insulin signaling networks
por: Lin, Yang-Chi-Dung, et al.
Publicado: (2020)

Integrated multi‐omic data and analyses reveal the pathways underlying key ornamental traits in carnation flowers
por: Zhang, Xiaoni, et al.
Publicado: (2022)

KeyPathwayMinerWeb: online multi-omics network enrichment
por: List, Markus, et al.
Publicado: (2016)

Multi-Omics Profiling in PGM3 and STAT3 Deficiencies: A Tale of Two Patients
por: Jacob, Minnie, et al.
Publicado: (2023)

Editorial: Multi-Omics Approaches to Study Signaling Pathways
por: Sharma, Jyoti, et al.
Publicado: (2020)

Signaling mechanisms in renal compensatory hypertrophy revealed by multi-omics
por: Kikuchi, Hiroaki, et al.
Publicado: (2023)

Multi-Omics Profiling for Health
por: Babu, Mohan, et al.
Publicado: (2023)

Multi-Omics Profiling Identifies Risk Hypoxia-Related Signatures for Ovarian Cancer Prognosis
por: Chen, Xingyu, et al.
Publicado: (2021)

Multi-omics Comparative Analysis Reveals Multiple Layers of Host Signaling Pathway Regulation by the Gut Microbiota
por: Manes, Nathan P., et al.
Publicado: (2017)

mitch: multi-contrast pathway enrichment for multi-omics and single-cell profiling data
por: Kaspi, Antony, et al.
Publicado: (2020)

Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer
por: Lu, Di, et al.
Publicado: (2022)

Multi-omics Data and Analytics Integration in Ovarian Cancer
por: Bhardwaj, Archana, et al.
Publicado: (2020)

Multi-omic profiling of plasma reveals molecular alterations in children with COVID-19
por: Wang, Chong, et al.
Publicado: (2021)

Editorial: Multi-omics profiling of unique niches to reveal the microbial and metabolite composition
por: Kumar, Roshan, et al.
Publicado: (2022)

Multi‐omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer
por: Stentenbach, Maike, et al.
Publicado: (2023)

Multi-omics profiling reveals rhythmic liver function shaped by meal timing
por: Huang, Rongfeng, et al.
Publicado: (2023)

Multi-omics reveals aging-related pathway in natural aging mouse liver
por: Tang, Cong-min, et al.
Publicado: (2023)

Multi-Omic Profiling of Multi-Biosamples Reveals the Role of Amino Acid and Nucleotide Metabolism in Endometrial Cancer
por: Yi, Runqiu, et al.
Publicado: (2022)

Biomarkers and key pathways in atrial fibrillation associated with mitral valve disease identified by multi-omics study
por: Li, Ming-Yang, et al.
Publicado: (2021)

Multi-omics Pathways Workflow (MOPAW): An Automated Multi-omics Workflow on the Cancer Genomics Cloud
por: Nguyen, Trinh, et al.
Publicado: (2023)

Spatial heterogeneity of infiltrating T cells in high-grade serous ovarian cancer revealed by multi-omics analysis
por: Yang, Bin, et al.
Publicado: (2022)

Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures
por: Kan, Zhengyan, et al.
Publicado: (2018)

Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19
por: Wilk, Aaron J., et al.
Publicado: (2021)

Multi-omic Profiling Reveals Early Immunological Indicators for Identifying COVID-19 Progressors
por: Drake, Katherine A., et al.
Publicado: (2023)

Raltegravir: The evidence of its therapeutic value in HIV-1 infection
por: Ramkumar, Kavya, et al.
Publicado: (2010)

Advances in single-cell multi-omics profiling
por: Bai, Dongsheng, et al.
Publicado: (2021)

Multi-omics profiling approach in food allergy
por: Devonshire, Ashley, et al.
Publicado: (2023)

Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer
por: Grunt, Thomas W., et al.
Publicado: (2020)

A Multi-Omics Analysis of Mucosal-Associated-Invariant T Cells Reveals Key Drivers of Distinct Modes of Activation
por: Schubert, Kristin, et al.
Publicado: (2021)

Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways
por: Ho, Won Jin, et al.
Publicado: (2021)

STAT1 is a key gene in a gene regulatory network related to immune phenotypes in bladder cancer: An integrative analysis of multi‐omics data
por: Weng, Hong, et al.
Publicado: (2021)

MOPA: An integrative multi-omics pathway analysis method for measuring omics activity
por: Jeon, Jaemin, et al.
Publicado: (2023)

Multi-OMIC profiling of survival and metabolic signaling networks in cells subjected to photodynamic therapy
por: Weijer, Ruud, et al.
Publicado: (2016)

Prognostic value of key genes of the JAK-STAT signaling pathway in patients with cutaneous melanoma
por: Pan, Fuqiang, et al.
Publicado: (2020)

An Integrated Multi-Omics Analysis Defines Key Pathway Alterations in a Diet-Induced Obesity Mouse Model
por: Sundekilde, Ulrik K., et al.
Publicado: (2020)

Multi-omics analysis of the Indian ovarian cancer cohort revealed histotype-specific mutation and gene expression patterns
por: Mhatre, Anisha, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mcjt3uotqnv1clpg7aiq3ssmfq