Cargando…

Chronic myelogenous leukemia cells remodel the bone marrow niche via exosome-mediated transfer of miR-320

Rationale: Reciprocal interactions between leukemic cells and bone marrow mesenchymal stromal cells (BMMSC) remodel the normal niche into a malignant niche, leading to leukemia progression. Exosomes have emerged as an essential mediator of cell-cell communication. Whether leukemic exosomes involved...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Xiaotong, Wan, Zhuo, Wei, Mengying, Dong, Yan, Zhao, Yingxin, Chen, Xutao, Li, Zhelong, Qin, Weiwei, Yang, Guodong, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735391/
https://www.ncbi.nlm.nih.gov/pubmed/31534508
http://dx.doi.org/10.7150/thno.34813