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Chronic myelogenous leukemia cells remodel the bone marrow niche via exosome-mediated transfer of miR-320
Rationale: Reciprocal interactions between leukemic cells and bone marrow mesenchymal stromal cells (BMMSC) remodel the normal niche into a malignant niche, leading to leukemia progression. Exosomes have emerged as an essential mediator of cell-cell communication. Whether leukemic exosomes involved...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735391/ https://www.ncbi.nlm.nih.gov/pubmed/31534508 http://dx.doi.org/10.7150/thno.34813 |