Cargando…

CPX Targeting DJ-1 Triggers ROS-induced Cell Death and Protective Autophagy in Colorectal Cancer

Rationale: Colorectal cancer (CRC) is one of the most common cancers worldwide. Ciclopirox olamine (CPX) has recently been identified to be a promising anticancer candidate; however, novel activities and detailed mechanisms remain to be uncovered. Methods: The cytotoxic potential of CPX towards CRC...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Jing, Zhang, Lu, Wang, Meng, Zhou, Li, Feng, Xuping, Yu, Linli, Lan, Jiang, Gao, Wei, Zhang, Chundong, Bu, Youquan, Huang, Canhua, Zhang, Haiyuan, Lei, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735393/
https://www.ncbi.nlm.nih.gov/pubmed/31534504
http://dx.doi.org/10.7150/thno.34663