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CPX Targeting DJ-1 Triggers ROS-induced Cell Death and Protective Autophagy in Colorectal Cancer
Rationale: Colorectal cancer (CRC) is one of the most common cancers worldwide. Ciclopirox olamine (CPX) has recently been identified to be a promising anticancer candidate; however, novel activities and detailed mechanisms remain to be uncovered. Methods: The cytotoxic potential of CPX towards CRC...
Autores principales: | Zhou, Jing, Zhang, Lu, Wang, Meng, Zhou, Li, Feng, Xuping, Yu, Linli, Lan, Jiang, Gao, Wei, Zhang, Chundong, Bu, Youquan, Huang, Canhua, Zhang, Haiyuan, Lei, Yunlong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735393/ https://www.ncbi.nlm.nih.gov/pubmed/31534504 http://dx.doi.org/10.7150/thno.34663 |
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