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Extracellular vesicles expressing a single-chain variable fragment of an HIV-1 specific antibody selectively target Env(+) tissues

Rationale: Antiretroviral therapy can effectively suppress HIV-1 replication in the peripheral blood to an undetectable level. However, elimination of the latent virus in reservoirs remains a challenge and is a major obstacle in the treatment of HIV-1-infected patients. Exosomes exhibit huge promise...

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Detalles Bibliográficos
Autores principales: Zou, Xue, Yuan, Meng, Zhang, Tongyu, Wei, Hongxia, Xu, Shijie, Jiang, Na, Zheng, Nan, Wu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735399/
https://www.ncbi.nlm.nih.gov/pubmed/31534509
http://dx.doi.org/10.7150/thno.33925