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The cystathionine γ-lyase/hydrogen sulfide pathway mediates the trimetazidine-induced protection of H9c2 cells against hypoxia/reoxygenation-induced apoptosis and oxidative stress

OBJECTIVE: Trimetazidine is a piperazine-derived metabolic agent. It exerts cardioprotective effects against myocardial ischemia/reperfusion (I/R) injury. In addition, studies confirm that the cystathionine γ-lyase (CSE)/hydrogen sulfide (H(2)S) pathway serves a beneficent role in attenuating myocar...

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Detalles Bibliográficos
Autores principales: Zheng, Wenqing, Liu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735432/
https://www.ncbi.nlm.nih.gov/pubmed/31475956
http://dx.doi.org/10.14744/AnatolJCardiol.2019.83648