Prostaglandin E(2) induces DNA hypermethylation in gastric cancer in vitro and in vivo

Rationale: Prostaglandin E(2) (PGE(2)) is a pro-inflammatory eicosanoid up-regulated in gastric cancer (GC). However, its impact on epigenetic dysfunction in the process of gastric carcinogenesis is unknown. In this study, we investigate the role of PGE(2) in DNA methylation in gastric epithelium in...

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Detalles Bibliográficos
Autores principales: Wong, Chi Chun, Kang, Wei, Xu, Jiaying, Qian, Yun, Luk, Simson Tsz Yat, Chen, Huarong, Li, Weilin, Zhao, Liuyang, Zhang, Xiaoming, Chiu, Phlip WY, Ng, Enders KW, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735505/
https://www.ncbi.nlm.nih.gov/pubmed/31534549
http://dx.doi.org/10.7150/thno.35766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735505/
https://www.ncbi.nlm.nih.gov/pubmed/31534549
http://dx.doi.org/10.7150/thno.35766

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