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Exosome-dependent immune surveillance at the metastatic niche requires BAG6 and CBP/p300-dependent acetylation of p53

Extracellular vesicles released by tumor cells contribute to the reprogramming of the tumor microenvironment and interfere with hallmarks of cancer including metastasis. Notably, melanoma cell-derived EVs are able to establish a pre-metastatic niche in distant organs, or on the contrary, exert anti-...

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Detalles Bibliográficos
Autores principales: Schuldner, Maximiliane, Dörsam, Bastian, Shatnyeva, Olga, Reiners, Katrin S., Kubarenko, Andriy, Hansen, Hinrich P., Finkernagel, Florian, Roth, Katrin, Theurich, Sebastian, Nist, Andrea, Stiewe, Thorsten, Paschen, Annette, Knittel, Gero, Reinhardt, Hans C., Müller, Rolf, Hallek, Michael, von Strandmann, Elke Pogge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735508/
https://www.ncbi.nlm.nih.gov/pubmed/31534536
http://dx.doi.org/10.7150/thno.36378