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Kidney-targeted rhein-loaded liponanoparticles for diabetic nephropathy therapy via size control and enhancement of renal cellular uptake

The optimization of nanoparticle size for passing through glomerular filtration membrane, inefficient renal cellular uptake and rapid urinary excretion of nanoparticles are the major obstacles for renal disease treatment via a nanoparticle delivery system. Herein, we propose a concept of a two-step...

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Detalles Bibliográficos
Autores principales: Wang, Guowei, Li, Qunying, Chen, Danfei, Wu, Bihan, Wu, Yulian, Tong, Weijun, Huang, Pintong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735513/
https://www.ncbi.nlm.nih.gov/pubmed/31534545
http://dx.doi.org/10.7150/thno.37538