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Mitochondrial membrane anchored photosensitive nano-device for lipid hydroperoxides burst and inducing ferroptosis to surmount therapy-resistant cancer

Rationale: Ferroptosis is a regulated process of cell death caused by iron-dependent accumulation of lipid hydroperoxides (LPO). It is sensitive to epithelial-to-mesenchymal transition (EMT) cells, a well-known therapy-resistant state of cancer. Previous studies on nanomaterials did not investigate...

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Detalles Bibliográficos
Autores principales: Sang, Mangmang, Luo, Renjie, Bai, Yidan, Dou, Jun, Zhang, Zhongtao, Liu, Fulei, Feng, Feng, Xu, Jian, Liu, Wenyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735518/
https://www.ncbi.nlm.nih.gov/pubmed/31534546
http://dx.doi.org/10.7150/thno.36283