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CAV1 - GLUT3 signaling is important for cellular energy and can be targeted by Atorvastatin in Non-Small Cell Lung Cancer

Background: The development of molecular targeted therapies, such as EGFR-TKIs, has positively impacted the management of EGFR mutated NSCLC. However, patients with innate and acquired resistance to EGFR-TKIs still face limited effective therapeutic options. Statins are the most frequently prescribe...

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Detalles Bibliográficos
Autores principales: Ali, Azhar, Levantini, Elena, Fhu, Chee Wai, Teo, Jun Ting, Clohessy, John G., Goggi, Julian L., Wu, Chan-shuo, Chen, Leilei, Chin, Tan Min, Tenen, Daniel G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735519/
https://www.ncbi.nlm.nih.gov/pubmed/31534543
http://dx.doi.org/10.7150/thno.35805