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Mesenchymal Stem Cell–Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA/2J Mouse Model of Glaucoma

PURPOSE: To determine if bone marrow-derived stem cell (BMSC) small extracellular vesicles (sEV) promote retinal ganglion cell (RGC) neuroprotection in the genetic DBA/2J mouse model of glaucoma for 12 months. METHODS: BMSC sEV and control fibroblast-derived sEV were intravitreally injected into 3-m...

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Detalles Bibliográficos
Autores principales: Mead, Ben, Ahmed, Zubair, Tomarev, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735616/
https://www.ncbi.nlm.nih.gov/pubmed/30452601
http://dx.doi.org/10.1167/iovs.18-25310