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An EGFP-marked recombinant lactobacillus oral tetravalent vaccine constitutively expressing α, ϵ, β1, and β2 toxoids for Clostridium perfringens elicits effective anti-toxins protective immunity
Clostridium perfringens is a common opportunistic pathogen endangering livestock and poultry breeds. Here, using enhanced green fluorescent protein as screening marker, a recombinant lactobacillus tetravalent vaccine constitutively expressing α, ϵ, β1, and β2 toxoids of C. perfringens was developed,...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735629/ https://www.ncbi.nlm.nih.gov/pubmed/31429624 http://dx.doi.org/10.1080/21505594.2019.1653720 |