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COmplexome Profiling ALignment (COPAL) reveals remodeling of mitochondrial protein complexes in Barth syndrome

MOTIVATION: Complexome profiling combines native gel electrophoresis with mass spectrometry to obtain the inventory, composition and abundance of multiprotein assemblies in an organelle. Applying complexome profiling to determine the effect of a mutation on protein complexes requires separating tech...

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Detalles Bibliográficos
Autores principales: Van Strien, Joeri, Guerrero-Castillo, Sergio, Chatzispyrou, Iliana A, Houtkooper, Riekelt H, Brandt, Ulrich, Huynen, Martijn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735710/
https://www.ncbi.nlm.nih.gov/pubmed/30649188
http://dx.doi.org/10.1093/bioinformatics/btz025