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COmplexome Profiling ALignment (COPAL) reveals remodeling of mitochondrial protein complexes in Barth syndrome
MOTIVATION: Complexome profiling combines native gel electrophoresis with mass spectrometry to obtain the inventory, composition and abundance of multiprotein assemblies in an organelle. Applying complexome profiling to determine the effect of a mutation on protein complexes requires separating tech...
Autores principales: | Van Strien, Joeri, Guerrero-Castillo, Sergio, Chatzispyrou, Iliana A, Houtkooper, Riekelt H, Brandt, Ulrich, Huynen, Martijn A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735710/ https://www.ncbi.nlm.nih.gov/pubmed/30649188 http://dx.doi.org/10.1093/bioinformatics/btz025 |
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