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Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice

Inhibition of 5α-reductases impairs androgen and glucocorticoid metabolism and induces insulin resistance in humans and rodents. The contribution of hepatic glucocorticoids to these adverse metabolic changes was assessed using a liver-selective glucocorticoid receptor (GR) antagonist, A-348441. Mice...

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Detalles Bibliográficos
Autores principales:	Mak, Tracy C S, Livingstone, Dawn E W, Nixon, Mark, Walker, Brian R, Andrew, Ruth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735737/ https://www.ncbi.nlm.nih.gov/pubmed/31199473 http://dx.doi.org/10.1210/en.2019-00236

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