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The Critical Role of Codon Composition on the Translation Efficiency Robustness of the Hepatitis A Virus Capsid

Hepatoviruses show an intriguing deviated codon usage, suggesting an evolutionary signature. Abundant and rare codons in the cellular genome are scarce in the human hepatitis A virus (HAV) genome, while intermediately abundant host codons are abundant in the virus. Genotype–phenotype maps, or fitnes...

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Detalles Bibliográficos
Autores principales: D’Andrea, Lucía, Pérez-Rodríguez, Francisco-Javier, de Castellarnau, Montserrat, Guix, Susana, Ribes, Enric, Quer, Josep, Gregori, Josep, Bosch, Albert, Pintó, Rosa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735747/
https://www.ncbi.nlm.nih.gov/pubmed/31290967
http://dx.doi.org/10.1093/gbe/evz146