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The Critical Role of Codon Composition on the Translation Efficiency Robustness of the Hepatitis A Virus Capsid
Hepatoviruses show an intriguing deviated codon usage, suggesting an evolutionary signature. Abundant and rare codons in the cellular genome are scarce in the human hepatitis A virus (HAV) genome, while intermediately abundant host codons are abundant in the virus. Genotype–phenotype maps, or fitnes...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735747/ https://www.ncbi.nlm.nih.gov/pubmed/31290967 http://dx.doi.org/10.1093/gbe/evz146 |