Differences in mutational processes and intra-tumour heterogeneity between organs: The local selective filter hypothesis

Extensive diversity (genetic, cytogenetic, epigenetic and phenotypic) exists within and between tumours, but reasons behind these variations, as well as their consistent hierarchical pattern between organs, are poorly understood at the moment. We argue that these phenomena are, at least partially, e...

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Detalles Bibliográficos
Autores principales: Giraudeau, Mathieu, Sepp, Tuul, Ujvari, Beata, Renaud, François, Tasiemski, Aurélie, Roche, Benjamin, Capp, Jean-Pascal, Thomas, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735757/
https://www.ncbi.nlm.nih.gov/pubmed/31528343
http://dx.doi.org/10.1093/emph/eoz017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735757/
https://www.ncbi.nlm.nih.gov/pubmed/31528343
http://dx.doi.org/10.1093/emph/eoz017

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