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TERC promotes cellular inflammatory response independent of telomerase

TERC is an RNA component of telomerase. However, TERC is also ubiquitously expressed in most human terminally differentiated cells, which don’t have telomerase activity. The function of TERC in these cells is largely unknown. Here, we report that TERC enhances the expression and secretion of inflamm...

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Detalles Bibliográficos
Autores principales: Liu, Haiying, Yang, Yiding, Ge, Yuanlong, Liu, Juanhong, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735767/
https://www.ncbi.nlm.nih.gov/pubmed/31294790
http://dx.doi.org/10.1093/nar/gkz584