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The dynamics of forming a triplex in an artificial telomere inferred by DNA mechanics

A telomere carrying repetitive sequences ends with a single-stranded overhang. The G-rich overhang could fold back and bind in the major groove of its upstream duplex, forming an antiparallel triplex structure. The telomeric triplex has been proposed to function in protecting chromosome ends. Howeve...

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Detalles Bibliográficos
Autores principales: Li, Ning, Wang, Junli, Ma, Kangkang, Liang, Lin, Mi, Lipei, Huang, Wei, Ma, Xiaofeng, Wang, Zeyu, Zheng, Wei, Xu, Linyan, Chen, Jun-Hu, Yu, Zhongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735771/
https://www.ncbi.nlm.nih.gov/pubmed/31114915
http://dx.doi.org/10.1093/nar/gkz464