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A hidden human proteome encoded by ‘non-coding’ genes

It has been a long debate whether the 98% ‘non-coding’ fraction of human genome can encode functional proteins besides short peptides. With full-length translating mRNA sequencing and ribosome profiling, we found that up to 3330 long non-coding RNAs (lncRNAs) were bound to ribosomes with active tran...

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Detalles Bibliográficos
Autores principales: Lu, Shaohua, Zhang, Jing, Lian, Xinlei, Sun, Li, Meng, Kun, Chen, Yang, Sun, Zhenghua, Yin, Xingfeng, Li, Yaxing, Zhao, Jing, Wang, Tong, Zhang, Gong, He, Qing-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735797/
https://www.ncbi.nlm.nih.gov/pubmed/31340039
http://dx.doi.org/10.1093/nar/gkz646