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Blast-Mediated Traumatic Brain Injury Exacerbates Retinal Damage and Amyloidosis in the APPswePSENd19e Mouse Model of Alzheimer's Disease

PURPOSE: Traumatic brain injury (TBI) is a risk factor for developing chronic neurodegenerative conditions including Alzheimer's disease (AD). The purpose of this study was to examine chronic effects of blast TBI on retinal ganglion cells (RGC), optic nerve, and brain amyloid load in a mouse mo...

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Detalles Bibliográficos
Autores principales: Harper, Matthew M., Hedberg-Buenz, Adam, Herlein, Judith, Abrahamson, Eric E., Anderson, Michael G., Kuehn, Markus H., Kardon, Randy H., Poolman, Pieter, Ikonomovic, Milos D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735799/
https://www.ncbi.nlm.nih.gov/pubmed/31247112
http://dx.doi.org/10.1167/iovs.18-26353