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Blast-Mediated Traumatic Brain Injury Exacerbates Retinal Damage and Amyloidosis in the APPswePSENd19e Mouse Model of Alzheimer's Disease
PURPOSE: Traumatic brain injury (TBI) is a risk factor for developing chronic neurodegenerative conditions including Alzheimer's disease (AD). The purpose of this study was to examine chronic effects of blast TBI on retinal ganglion cells (RGC), optic nerve, and brain amyloid load in a mouse mo...
Autores principales: | Harper, Matthew M., Hedberg-Buenz, Adam, Herlein, Judith, Abrahamson, Eric E., Anderson, Michael G., Kuehn, Markus H., Kardon, Randy H., Poolman, Pieter, Ikonomovic, Milos D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735799/ https://www.ncbi.nlm.nih.gov/pubmed/31247112 http://dx.doi.org/10.1167/iovs.18-26353 |
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