Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis

Mutations causing amyotrophic lateral sclerosis (ALS) clearly implicate ubiquitously expressed and predominantly nuclear RNA binding proteins, which form pathological cytoplasmic inclusions in this context. However, the possibility that wild-type RNA binding proteins mislocalize without necessarily...

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Detalles Bibliográficos
Autores principales: Tyzack, Giulia E, Luisier, Raphaelle, Taha, Doaa M, Neeves, Jacob, Modic, Miha, Mitchell, Jamie S, Meyer, Ione, Greensmith, Linda, Newcombe, Jia, Ule, Jernej, Luscombe, Nicholas M, Patani, Rickie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735815/
https://www.ncbi.nlm.nih.gov/pubmed/31368485
http://dx.doi.org/10.1093/brain/awz217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735815/
https://www.ncbi.nlm.nih.gov/pubmed/31368485
http://dx.doi.org/10.1093/brain/awz217

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