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Enzyme-free optical DNA mapping of the human genome using competitive binding

Optical DNA mapping (ODM) allows visualization of long-range sequence information along single DNA molecules. The data can for example be used for detecting long range structural variations, for aiding DNA sequence assembly of complex genomes and for mapping epigenetic marks and DNA damage across th...

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Detalles Bibliográficos
Autores principales: Müller, Vilhelm, Dvirnas, Albertas, Andersson, John, Singh, Vandana, KK, Sriram, Johansson, Pegah, Ebenstein, Yuval, Ambjörnsson, Tobias, Westerlund, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735870/
https://www.ncbi.nlm.nih.gov/pubmed/31165870
http://dx.doi.org/10.1093/nar/gkz489