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Molecular Chaperones Accelerate the Evolution of Their Protein Clients in Yeast
Protein stability is a major constraint on protein evolution. Molecular chaperones, also known as heat-shock proteins, can relax this constraint and promote protein evolution by diminishing the deleterious effect of mutations on protein stability and folding. This effect, however, has only been stab...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735891/ https://www.ncbi.nlm.nih.gov/pubmed/31297528 http://dx.doi.org/10.1093/gbe/evz147 |