OLGA: fast computation of generation probabilities of B- and T-cell receptor amino acid sequences and motifs

MOTIVATION: High-throughput sequencing of large immune repertoires has enabled the development of methods to predict the probability of generation by V(D)J recombination of T- and B-cell receptors of any specific nucleotide sequence. These generation probabilities are very non-homogeneous, ranging o...

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Detalles Bibliográficos
Autores principales: Sethna, Zachary, Elhanati, Yuval, Callan, Curtis G, Walczak, Aleksandra M, Mora, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735909/
https://www.ncbi.nlm.nih.gov/pubmed/30657870
http://dx.doi.org/10.1093/bioinformatics/btz035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735909/
https://www.ncbi.nlm.nih.gov/pubmed/30657870
http://dx.doi.org/10.1093/bioinformatics/btz035

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